Nicotine Vapor Method to Induce Nicotine Dependence in Rodents
نویسندگان
چکیده
منابع مشابه
Susceptibility to nicotine dependence: the Development and Assessment of Nicotine Dependence in Youth 2 study.
OBJECTIVES The purpose of this work was to identify characteristics that predict progression from the first inhalation of a cigarette to dependence. We studied a cohort of 1246 public school 6th-graders in 6 Massachusetts communities (mean age at baseline: 12.2 years). METHODS We conducted a 4-year prospective study using 11 interviews. We assessed 45 risk factors and measured diminished auto...
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Nicotine is a psychoactive ingredient in tobacco that significantly contributes to the harmful tobacco smoking habit. Nicotine dependence is more prevalent than dependence on any other substance. Preclinical research in animal models of the various aspects of nicotine dependence suggests a critical role of glutamate, g-aminobutyric acid (GABA), cholinergic and dopamine neurotransmitter interact...
متن کاملTranslational research in nicotine dependence.
Nicotine addiction accounts for 4.9 million deaths each year. Furthermore, although smoking represents a significant health burden in the United States, at present there are only three FDA-approved pharmacotherapies currently on the market: (1) nicotine replacement therapy, (2) bupropion, and (3) varenicline. Despite this obvious gap in the market, the complexity of nicotine addiction in additi...
متن کاملOral Nicotine Self-Administration in Rodents.
Nicotine addiction is a complex process that begins with self-administration. Consequently, this process has been studied extensively using animal models. A person is usually not called "smoker" if s/he has smoked for a week or a month in a lifetime; in general, a smoker has been smoking for many years. Furthermore, a smoker has free access to cigarettes and can smoke whenever she/he wants, pro...
متن کاملBehavioral responses to surveys about nicotine dependence.
Behavioral responses to surveys can significantly affect inferences about population prevalence unless correctly modeled statistically. An important case study is the prevalence of nicotine dependence, a formal psychiatric disorder satisfying clinical criteria. Data from the National Epidemiologic Survey on Alcohol and Related Conditions in the United States are used, along with a flexible semi...
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ژورنال
عنوان ژورنال: Current Protocols in Neuroscience
سال: 2017
ISSN: 1934-8584,1934-8576
DOI: 10.1002/cpns.34